Journal: Viruses
Article Title: Monocyte Dynamics in Chikungunya Fever: Sustained Activation and Vascular-Coagulation Pathway Involvement
doi: 10.3390/v17091224
Figure Lengend Snippet: Circulating markers of inflammation and vascular dysfunction. ( A – D ) Circulating levels of IL-6, TNF-α, IL-17A, and IL-10 in patients with CF during the acute (n = 46), post-acute (n = 4), chronic (n = 8) phases of infection, and in HD (n = 10). ( E , F ) Circulating levels of TF and TFPI in CF patients during the acute (n = 37), post-acute (n = 4), and chronic (n = 8) phases, and in HD (n = 10). ( G ) Circulating levels of VEGF in CF patients during the acute (n = 53), post-acute (n = 4) and chronic phases (n = 8), and in HD (n = 10). ( H ) Circulating levels of EGF in CF patients during the acute (n = 39), post-acute (n = 4), chronic phases (n = 8), and in HD (n = 10). ( I ) Circulating levels of PDGF-BB in CF patients during the acute (n = 43), post-acute (n = 4), chronic phases (n = 8), and in HD (n = 10). Data are presented as medians with interquartile ranges (IQR). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001; one-way ANOVA followed by Kruskal–Wallis test and Dunn’s multiple comparisons test and using the Mann–Whitney test.
Article Snippet: Circulating levels of TF and TFPI in HD and CHIKV-infected patients were measured using the Human Coagulation Factor II/Tissue Factor ELISA Kit (R&D Systems, Minneapolis, MN, USA) and the Human TFPI ELISA Kit (R&D Systems, Minneapolis, MN, USA), following the manufacturer’s instructions.
Techniques: Infection, MANN-WHITNEY